KRISP is reversing the brain drain and achieving scientific excellence, 15 Nature, Science and Lancet papers in three years, in Africa

SPOTLIGHT


Promotion Sanger


KRISP & AHRI News


KRISP News

KRISP NEWS

Promotion Sanger Sequencing at KRISP - Jan to Dec 2020

KRISP is running a Sanger Sequencing promotion to celebrate the launch of two new Sanger Sequencers (ABI 3730xl and 3500). Unbelievable prices for 2020. Capillary electrophoresis only – R 25 (per sample well). Sequencing of PCR purified amplicons – R 45 (per primer). Sequencing of PCR unpurified amplicons – R 75 (per primer).


KRISP Join Stanford SPARK Global Program and creates Durban SPARK Innovation Breakfast Monthly Meeting

KRISP at UKZN partner with Stanford University on a global innovation program: SPARK GLOBAL: Translational Scientists without borders. As part of this program we run a monthly meeting (first Wednesday of EVERY MONTH) to discuss innovation, select and mentor start-ups that can produce translational research.


KRISP Service Brochure 2020

KRISP expanded its genomics service offers. Our DNA sequencing services incorporate internal quality control (IQC), external quality assurance (EQA) and procedures are validated and performed by HPCSA-accredited scientists. Here you can access a detailed brochure of the genomics services we provide in Africa.


New study shows 43% drop in rate of new HIV infections

New research from the Africa Health Research Institute (AHRI) in collaboration with KRISP shows a 43% decrease in the rate of new HIV infections between 2012 and 2017 in the Hlabisa area of northern KwaZulu-Natal (KZN), South Africa.


Science Through the Lens of Photography

Lifeblood, an exhibition of photographs by Mr Samora Chapman at the Community Art Gallery in Durban. Curated by UKZN Professor and Director of the KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP) Tulio de Oliveira, it aimed to highlight the diversity of humans, plants and animals in South Africa.


KRISP Newsletter Dec 2019: Conservation Genomics and big decline in the overall HIV incidence rate in northern KZN!

This month, we report on a Nature Communications paper with AHRI that report a 43% decline in the overall HIV incidence rate in northern KZN. We also hosted a leading conservation genomics scientist and organized many talks and events. We went to Drakensberg for our strategic meeting, released the KRISP Wellness program and even went to Hamburg, Germany, to compete in the finals of the Upgrade my NGS Competition.


KRISP Wellness

In today’s world, health and wellness are critical components of a productive work environment and a happy workforce. To often, these topics are misunderstood or ignored in an organisation’s drive for results and profit. Health and wellness can also not be viewed in isolation of each other, as each feeds into and supports the other. Health is a state of body, and wellness is a state of being


KRISP and Genomics Africa hosted a leading Conservation Geneticist in South Africa

Prof. Frandsen, who published a paper in Science on conservation genomics in Nov 2019, has worked with KRISP & Genomics Africa to identify DNA sequencing services that we offer the conservation community in Africa.


KRISP Newsletter Dec 2019: Conservation Genomics and big decline in the overall HIV incidence rate in northern KZN!

This month, we focus on a key Nature Communications paper that report a 43% decline in the overall HIV incidence rate in northern KZN. We also hosted a leading conservation genomics scientist and organized many talks and events. We went to Drakensberg for our strategic meeting, released the KRISP Wellness program and even went to Hamburg, Germany, to compete in the finals of the Upgrade my NGS Competition.


KRISP 2020 - Strategy Meeting

At the end of November, the KRISP team traded their lab coats and laptops for hiking boots and hats, as they travelled up to the Sani Pass Premier Resort for a three-day strategy session


KRISP PAPERS

Quantifying HIV transmission flow between high-prevalence hotspots and surrounding communities: a population-based study in Rakai, Uganda.
Ratmann O, Kagaayi J, Hall M, Golubchick T, Kigozi G, Xi X, Wymant C, Nakigozi G, Abeler-Dörner L, Bonsall D, Gall A, Hoppe A, Kellam P, Bazaale J, Kalibbala S, Laeyendecker O, Lessler J, Nalugoda F, Chang LW, de Oliveira T, Pillay D, Quinn TC, Reynolds SJ, Spencer SEF, Ssekubugu R, Serwadda D, Wawer MJ, Gray RH, Fraser C, Grabowski MK, on behalf of the Rakai Health Sciences Program and the Pangea HIV Consortium, Lancet HIV (2020), https://doi.org/10.1016/ S2352-3018(19)30378-9:.


HIV seroconcordance among heterosexual couples in rural KwaZulu-Natal, South Africa: a population-based analysis.
Kim HY, Harling G, Vandormael A, Tomita A, Cuadros DF, Bärnighausen T, Tanser F, J Int AIDS Soc. (2020), 23(1):e25432. doi: 10.1002/jia2.25432:.


Persistence of chikungunya ECSA genotype and local outbreak in an upper medium class neighborhood in Northeast Brazil.
Goes de Jesus J, da Luz Wallau G, Lima Maia M, Xavier J, Oliveira Lima MA, Fonseca V, Salgado de Abreu A, Fraga de Oliveira Tosta S, Ramos do Amaral H, Andrade Barbosa Lima I, Viana Silva P, Carlos Dos Santos D, Sousa de Oliveira A, Campos de Souza S, Barreto Falcão M, Cerqueira E, Ceschini Machado L, Sobral MC, Teodoro Rezende TM, Ribeiro Pereira M, Mota Pereira F, Pereira Gusmão Maia Z, Freitas de Oliveira França R, Luiz de Abreu A, Campelo de Albuquerque E Melo CF, Rodrigues Faria N, Venâncio da Cunha R, Giovanetti M, Alcantara LCJ, PLoS ONE (2020), 15(1):e0226098. doi: 10.1371/journal.pone.0226098:.


Return of the founder Chikungunya virus to its place of introduction into Brazil is revealed by genomic characterization of exanthematic disease cases..
Pereira Gusmão Maia Z, Mota Pereira F, do Carmo Said RF, Fonseca V, Gräf T, de Bruycker Nogueira F, Brandão Nardy V, Xavier J, Lima Maia M, Abreu AL, Campelo de Albuquerque CF, Kleber Oliveira W, Croda J, de Filippis AMB, Venancio Cunha R, Lourenço J, de Oliveira T, Faria NR, Junior Alcantara LC, Giovanetti M, Emerg Microbes Infect. (2020), 9(1):53-57. doi: 10.1080/22221751.2019.1701954:.


Analysis of the microarray gene expression for breast cancer progression after the application modified logistic regression.
Morais-Rodrigues F, Silv Erio-Machado R, Kato RB, Rodrigues DLN, Valdez-Baez J, Fonseca V, San EJ, Gomes LGR, Dos Santos RG, Vinicius Canário Viana M, da Cruz Ferraz Dutra J, Teixeira Dornelles Parise M, Parise D, Campos FF, de Souza SJ, Ortega JM, Barh D, Ghosh P, Azevedo VAC, Dos Santos MA, Gene (2020), 144168. doi: 10.1016/j.gene.2019.144168.:.


The pharmacokinetic properties of HIV-1 protease inhibitors: A computational perspective on herbal phytochemicals..
Kehinde I, Ramharack P, Nlooto M, Gordon M, Heliyon (2019), 5(10):e02565. doi: 10.1016/j.heliyon.2019.e02565:.


KRISP VIDEOS

KRISP Public Engagement Photography Exhibition Lifeblood: A Showcase of African Diversity by Samora Chapman
By: Paul and Tulio de Oliveira

KRISP TEAM

KRISP BLOGS


KRISP TOOLS

2019-08-20
Version: 1


ArboTyping: Dengue Virus Typing Tool

This is a beta version of our Dengue Virus Typing tool. For the mean time, this tool should be used for evaluation only. Please send feedback to Tulio de Oliveira.


2019-08-20
Version: 1


ArboTyping: Zika Typing Tool

This is the first version of the Zika typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.


2019-08-20
Version: 1


ArboTyping: Chikungunya Typing Tool

This is the first version of the Chikungunya typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.


2019-08-20
Version: 1


ArboTyping: Yellow Fever Virus Typing Tool

This is the first version of the Yellow Fever typing tool, which uses phylogenetic analysis to identify the species and genotype of the virus.


2019-04-20
Version: 1


Genome Detective

This is the first version of our Arbovirus typing tool for Chikungunya, Dengue, Yellow Fever and Zika


2019-02-12
Version: 3


REGA HIV Subtyping Tool V3 - Belgium Mirror

Phylogenetic tool to identify the HIV-1 subtypes and recombinants. Query sequences are analysed for recombination using bootscanning methods. The version 3 contains new CRFs (CRF01_AE to CRF47_BF).



KRISP has been created by the coordinated effort of the University of KwaZulu-Natal (UKZN), the Technology Innovation Agency (TIA) and the South African Medical Research Countil (SAMRC).



Location: K-RITH Tower Building
Nelson R Mandela School of Medicine, UKZN
719 Umbilo Road, Durban, South Africa.
Director: Prof. Tulio de Oliveira