Dr. Veron Ramsuran

My work focus on host factors associating with HIV disease, with special interest on the Human Leukocyte Antigen (HLA) genes. I am also very interested epigenetics techniques such as CRISPR and DNA methylation.

Contact Details:

Email: Veron.ramsuran@gmail.com

Telephone: +27 (0) 31 260 4898

Background:

Dr. Veron Ramsuran graduated with a PhD from the University of KwaZulu-Natal where he examined host factors associating with HIV disease. He spent almost 70% of his PhD in two international laboratories, i.e. Fred Hutchinson Cancer Research Center and The University of Texas Health Science Center at San Antonio. After completion of his PhD he was recruited to join the Ragon Institute of MGH, MIT and Harvard as a post-doctoral research fellow, he had a joint affiliation with a contractor to the NIH and NCI. His appointment was under the mentorship of Dr. Mary Carrington. His work continued to focus on host factors associating with HIV disease, with special interest on the Human Leukocyte Antigen (HLA) genes. After completing 5 years in these institutes Dr. Ramsuran returned to South Africa where he is currently a Senior Lecturer within the University of KwaZulu-Natal.

Current Affiliations:

Group leader: KRISP - KwaZulu-Natal Research and Innovation Sequencing Platform, UKZN, Durban, South Africa.

- Senior Lecturer: School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Education:

- Post Doctorate: Ragon Institute of MGH, MIT and Harvard and National Cancer Institute (NCI) a division of the National Institute of Health (NIH) (2012-2016).

- PhD in Genetics: HIV Pathogenesis Programme and University of KwaZulu-Natal (2007-2011).

- MSc in Genetics: School of Life Sciences, University of KwaZulu-Natal (2006).


Open access pdf Publications

Sequence and Phylogenetic Analysis of the Untranslated Promoter Regions for HLA Class I Genes.
Ramsuran V, Hernandez-Sanchez PG, O'hUigin C, Sharma G, Spence N, Augusto DG, Gao X, Garcia-Sepulveda CA, Kaur G, Mehra NK, Carrington M,, J Immunol (2017), pii: 1601679:.

HLA-C Level Is Regulated by a Polymorphic Oct1 Binding Site in the HLA-C Promoter Region.
Vince N, Li H, Ramsuran V, Naranbhai V, Duh FM, Fairfax BP, Saleh B, Knight JC, Anderson SK, Carrington M, Am J Hum Genet (2016), 99(6):1353-1358.

Epigenetic regulation of differential HLA-A allelic expression levels.
Ramsuran V, Kulkarni S, O'huigin C, Yuki Y, Augusto DG, Gao X, Carrington M, Hum Mol Genet (2015), 24(15):4268-75.

Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.
Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK., Proc Natl Acad Sci U S A (2015), 112(34):E4762-71.

Expression of the CCR5 HIV co-receptor in women with genital schistosomiasis.
Kleppa E, Ramsuran V, Zulu S, Karlsen GH, Bere A, Passmore JA, Ndhlovu P, Lillebo K, Holmen SD, Onsrud M, Gundersen SG, Taylor M, Kjetland EF, Ndung'u T, 16th ICID Abstracts / International Journal of Inf (2014), 21S:1-460.

Effect of female genital schistosomiasis and anti-schistosomal treatment on monocytes, CD4+ T-cells and CCR5 expression in the female genital tract.
Kleppa E, Ramsuran V, Zulu S, Karlsen GH, Bere A, Passmore JA, Ndhlovu P, Lillebo K, Holmen SD, Onsrud M, Gundersen SG, Taylor M, Kjetland EF, Ndung'u T, PLoS One (2014), 9(6):e98593.

Genetic interplay between HLA-C and MIR148A in HIV control and Crohn disease.
Kulkarni S, Qi Y, O'hUigin C, Pereyra F, Ramsuran V, McLaren P, Fellay J, Nelson G, Chen H, Liao W, Bass S, Apps R, Gao X, Yuki Y, Lied A, Ganesan A, Hunt PW, Deeks SG, Wolinsky S, Walker BD, Carrington M, Proc Natl Acad Sci U S A (2013), 110(51):20705-10.

Influence of variations in CCL3L1 and CCR5 on tuberculosis in a northwestern Colombian population.
Mamtani M, Mummidi S, Ramsuran V, Pham MH, Maldonado R, Begum K, Valera MS, Sanchez R, Castiblanco J, Kulkarni H, Ndung'u T, He W, Anaya JM, Ahuja SK, J Infect Dis (2011), 203(11):1590-4.

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.
Ramsuran V, Kulkarni H, He W, Mlisana K, Wright EJ, Werner L, Castiblanco J, Dhanda R, Le T, Dolan MJ, Guan W, Weiss RA, Clark RA, Karim SS, Ahuja SK, Ndung'u T, Clin Infect Dis. (2011), 52(10):1248-56.

KRISP News Section from Bioafrica and SATuRN websites
News News Description and Link

KRISP News Section from Bioafrica and SATuRN websites

KRISP News

Durban at the forefront of DNA research - KwaZulu-Natal Research and Innovation Sequencing Platform - KRISP

KRISP News - 2017-07-15

By Arthi Gopi, Independent on Saturday Newspaper - KRISP atrracts the brightest - Durban is leading the way in DNA research, having attracted some of the brightest minds in the science field, in a new state-of-the-art lab in the city.


KRISP Talks

Seminar: Differential HLA-A Expression Levels and the Effect on HIV

KRISP Talks - 2017-01-27

KRISP Talks by Dr Veron Ramsuran, Senior Lecturer: College of Health Sciences, UKZN, 27 January 2017, K-RITH building, Nelson R Mandela School of Medicine, Durban, South Africa



KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), K-RITH Tower Building, Nelson R Mandela School of Medicine, UKZN

Contact: Prof. Tulio de Oliveira, Tel: +27 31 260 4898, Email: tuliodna@gmail.com & deoliveira@ukzn.ac.za

Page design updated 2015. Many of the pages were previously hosted at bioafrica.net.