Atypical mycobacterial spondylitis in HIV-negative patients identified by 16S rDNA genotyping. J Bone Joint Surg Br., 89(3) : 346-348 (2007).

Publication Latest Publications

Title: Atypical mycobacterial spondylitis in HIV-negative patients identified by 16S rDNA genotyping
Authors: Danaviah S, Govender S, Gordon ML, Cassol S. .
Journal: J Bone Joint Surg Br.,89(3) :346-348 (2007)
Number of citations (Google Scholar): 3

Abstract

Non-tuberculous mycobacterial infections pose a significant diagnostic and therapeutic challenge. We report two cases of such infection of the spine in HIV-negative patients who presented with deformity and neurological deficit. The histopathological features in both specimens were diagnostic of tuberculosis. The isolates were identified as Mycobacterium intracellulare and M. fortuitum by genotyping (MicroSeq 16S rDNA Full Gene assay) and as M. tuberculosis and a mycobacterium other than tuberculosis, respectively, by culture. There is a growing need for molecular diagnostic tools that can differentiate accurately between M. tuberculosis and atypical mycobacteria, especially in regions of the developing world which are experiencing an increase in non-tuberculous mycobacterial infections.

Download: Full text paper

Citation: Danaviah S, Govender S, Gordon ML, Cassol S. . Atypical mycobacterial spondylitis in HIV-negative patients identified by 16S rDNA genotyping J Bone Joint Surg Br.,89(3) :346-348 (2007).


Sexual partnership age pairings and risk of HIV acquisition in rural South Africa
Journal: AIDS (2017)

Incidence rate estimation, periodic testing and the limitations of the mid-point imputation approach
Journal: International Journal of Epidemiology (2017)

Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration
Journal: EBioMedicine (2017)
All publications...


KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), K-RITH Tower Building, Nelson R Mandela School of Medicine, UKZN

Contact: Prof. Tulio de Oliveira, Tel: +27 31 260 4898, Email: tuliodna@gmail.com & deoliveira@ukzn.ac.za

Page design updated 2013. Many of the pages were previously hosted at bioafrica.net.