15 minutes: KRISP Work at a Glance

In this new section of the krisp.org.za website, the idea is that anyone with 15 minutes to spare can learn about our work and its application in everyday life.

The South African COVID-19 Pregnancy Outcomes Study

KRISP News - 2020-05-29

The South African Obstetric Surveillance System Consortium in partnership with the SA MRC Maternal and Infant Health Strategies Unit and KRISP/UKZN invites clinicians from South African obstetric institutions to participate in this national study.


Report into a nosocomial outbreak of coronavirus disease 2019 (COVID-19) at Netcare St. Augustine’s Hospital

KRISP Open Report - 2020-05-22

This report presents the findings and recommendations of an investigation into a nosocomial outbreak of coronavirus disease 2019 (COVID-19) at St. Augustine’s Hospital in Durban, South Africa. The investigation began on 4 April after the identification of a number of confirmed COVID-19 cases and three deaths at the hospital. Investigation methods included medical record reviews, ward visits, and interviews with health care workers and management. A detailed timeline of patient cases was constructed to generate hypotheses as to the spread of infection through the hospital. In addition, DNA sequencing of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) nucleic acid extracted from nasopharyngeal and oropharyngeal swab samples was performed and phylogenetic analysis was conducted.


PRESS RELEASE: Findings and recommendations of the investigation into the Covid-19 outbreak at Netcare St Augustine’s Hospital led by UKZN team

Press release - 2020-05-20

The investigation found that between 9 March and 30 April 2020, there were 119 confirmed cases identified at St. Augustine’s Hospital (39 patients and 80 staff). Fifteen of the 39 patients died (case fatality rate 38.5%). The most plausible explanation for the outbreak is that there was a single introduction of the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2)


How one COVID-19 case at St Augustine’s Hospital led to 135 infections within 51 days – report

Bhekisisa - 2020-05-20

The coronavirus spread rapidly through Netcare St. Augustine’s Hospital and beyond and made up 14% of KwaZulu-Natal’s infections by the end of April. The study, seen by Bhekisisa, was conducted by researchers at the University of KwaZulu-Natal’s (UKZN) Nelson R. Mandela School of Medicine and the KwaZulu?Natal Research Innovation & Sequencing Platform, Krisp.


University probe finds over 100 Covid-19 cases at St Augustine's Hospital

JacarandaFM - 2020-05-20

An investigation has found there were 119 confirmed cases of coronavirus at Durban's St Augustine's Hospital by the end of last month. The probe into the Covid-19 outbreak at the hospital was led by a team at University of KwaZuu-Natal.


Netcare welcomes findings into Covid-19 outbreak at St Augustine's Hospital

Independent - 2020-05-20

Durban - The Netcare group has welcomed the findings of a report which investigated the outbreak of Covid-19 at the St Augustine's Hospital. On Wednesday, the investigative report was released and showed that between March 9 and April 30, there were 119 people – among them 39 patients and 80 staff members – who had confirmed cases identified at the hospital. Fifteen of the 39 patients died.



YouTube Videos

Sequencing SARS-CoV-2 in Africa in real-time to control COVID-19 outbreaks

From Tulio De Oliveira, Jennifer Giandhari and Sureshnee Pillay, date: 2020-05-20, duration: 00:03:22

COVID-19 Pandemic | Outcome of investigation into COVID-19 at Netcare St Augustine's Hospital

From Tulio de Oliveira, date: 2020-05-20, duration: 00:09:32

COVID-19 Question 3: How has South Africa's mortality rate been impacted by the pandemic?

From Richard Lessells, date: 2020-05-12, duration: 00:01:52

COVID-19 Question 2: What can we learn from the emerging COVID-19 deaths around the word?

From Richard Lessells, date: 2020-05-12, duration: 00:03:01


KRISP has been created by the coordinated effort of the University of KwaZulu-Natal (UKZN), the Technology Innovation Agency (TIA) and the South African Medical Research Countil (SAMRC).


Location: K-RITH Tower Building
Nelson R Mandela School of Medicine, UKZN
719 Umbilo Road, Durban, South Africa.
Director: Prof. Tulio de Oliveira